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Department of Epileptology and DZNE

Adresse:
German Center for Neurodegenerative Diseases (DZNE), Ludwig-Erhard-Allee 2, D-53105, Bonn/Germany
Telefon:
+49-228 28751605
Send an email.

Weitere Informationen

Education and degrees 

2003  
Doctoral degree, University of Bonn
2004
Approbation as Medical Doctor

 

Academic Career

2005-2007
Feodor-Lynen-Alexander von Humboldt Fellow, Department of Neurobiology and Physiology, Northwestern University, Chicago, Illinois
2008-2009
BONFOR-independent junior group leader, Department of Epileptology, University of Bonn
2009 Head of NRW Research group “Dendritic Integration in the CNS”, Department of Epileptology, University of Bonn
Since 2010 Parallel appointment as DZNE group leader, Research group "Neuronal Networks", Deutsches Zentrum für Neurodegenerative Erkrankungen, Bonn
2011 Juniorprofessor “Dendritic Pathophysiology” – University of Bonn/DZNE
2013 Professor (tenured) – University of Bonn/DZNE Bonn

 

Awards and Honors

2002  
Young investigator award, American Epilepsy Society
2003 Award of a ‘Summa cum laude’ for MD thesis work
2005   Alexander von Humboldt-Fellowship
2009  
Recipient of NRW Junior Research Group funding, Ministry of Education, Research, Innovation and Technology, Northrhine-Westfalia  

 

Memberships and professional functions:

* Society of Neuroscience, German Neuroscience Society, Review editor Frontiers in Neural Circuits

Most important publications

  1. Justus D, Dalügge D, Bothe S, Fuhrmann F, Hannes C, Kaneko H, Friedrichs D, Sosulina L, Schwarz I, Elliott D, Schoch S, Bradke F, Schwarz MK, Remy S. (2016) Glutamatergic synaptic integration of locomotion speed in the medial entorhinal cortex. Nat. Neurosci.,  Nov 28, doi: 10.1038/nn.4447 

  2. Schmid LC, Mittag M, Poll S, Steffen J, Wagner J, Geis HR, Schwarz I, Schmidt B, Schwarz MK, Remy S, Fuhrmann M. (2016). Dysfunction of Somatostatin-positive interneurons is associated with memory deficits in a mouse model of Alzheimer’s disease. Neuron. 92(1):114-125 

  3. Fuhrmann F, Justus D, Sosulina L, Kaneko H, Beutel T, Friedrichs D, Schoch S, Schwarz MK, Fuhrmann M, Remy S. (2015) Locomotion, Theta Oscillations, and the Speed-Correlated Firing of Hippocampal Neurons Are Controlled by a Medial Septal Glutamatergic Circuit. Neuron, 86(5), 1253-1264. 

  4. Wagner J, Krauss S, Shi S, Ryazanov S, Steffen J, Miklitz C, Leonov A, Kleinknecht A, Göricke B, Weishaupt JH, Weckbecker D, Reiner AM, Zinth W, Levin J, Ehninger D, Remy S, Kretzschmar HA, Griesinger C, Giese A, Fuhrmann M. (2015). Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies. Acta Neuropathol., (5): 619-631 

  5. Šišková S, Justus D, Kaneko H, Friedrichs D, Henneberg N, Beutel T, Pitsch J, Schoch S, Becker A, von der Kammer H, Remy S. (2014) Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer's disease Neuron, 84(5): 1023-1033. 

  6. Müller C, Beck H, Coulter D, Remy S. (2012) Inhibitory control of linear and supralinear dendritic excitation in CA1 pyramidal neurons Neuron, 75(5): 851-864. 

  7. Krüppel R, Remy S, Beck H. (2011) Dendritic integration in hippocampal dentate granule cells. Neuron, 71: 512-528. 

  8. Park JY, Remy S, Varela J, Cooper DC, Chung S, Kang HW, Lee JH and Spruston N. (2010) A post-burst afterdepolarization is mediated by group I mGluR-dependent upregulation of Ca(v)2.3 R-type calcium channels in CA1 pyramidal neurons. PLoS Biology, 8(11), e1000534. 

  9. Remy S, Csicsvari J, Beck H. (2009) Activity-dependent control of neuronal output by local and global dendritic spike attenuation. Neuron, 61: 906-916.

  10. Remy S, Spruston N. (2007) Dendritic spikes induce single-burst long-term potentiation. Proc. Natl. Acad. Sci. U.S.A (PNAS), 104(43): 17192-17197.
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