Prof. Dr. med. Albert Becker

Department of Neuropathology

Weitere Informationen

Education/Degrees

1989-1997 Medical schools at the Universities of Aachen, Charité Berlin and Bonn.
1997 Doctoral Thesis at the Charité, Humboldt University, Berlin
2004 Habilitation, University of Bonn

Academic and Clinical Career

06/1997 – 12/1997 Postdoctoral Fellow at the Dept. of Medical Genetics. Advisor: Prof. F.C. Luft, Franz-Volhard-Clinic, Humboldt University, Berlin
01/1998 – 06/1999 Resident, Dept. of Epileptology, University of Bonn
07/1999 – 12/1999 Resident, Dept. of Neuropathology, University of Bonn
01/2000 – 12/2001 Resident, Dept. of Pathology, University of Bonn
01/2002 – 01/2004 Head, Epilepsy Research Unit, Dept. of Neuropathology, University of Bonn
Since 02/2004 Assistant Medical Director, Department for Neuropathology, University of Bonn Medical Center
Since 07/2007 Associate Professor (tenured), Chair for Molecular Neuropathology, Dept. of Neuropathology, University of Bonn
Since 2013 Head of Section for Translational Epilepsy Research, Dept. of Neuropathology, University of Bonn
Since 2014 / 2015 Speaker of ‘Promotionskolleg’ SciMed (06/2014) and EKFS-NeuroImmunology (04/2016).

Awards

2003 Dr.-Volker-Helbig Prize for Epilepsy Research
2003 Young Investigator Award, International League Against Epilepsy
2004 Poster award at the Annual Meeting of the American Epilepsy Society

Most important publications

  1. Pabst M, Braganza O, Dannenberg H, Rosen J, van Loo K, Deisseroth K, Schoch S, Becker AJ, Beck H. (2016) Astrocytic intermediaries of septohippocampal cholinergic transmission.Neuron,  90(4): 853-865.
  2. Woitecki AM, Müller JA, van Loo KM, Sowade RF, Becker AJ, Schoch S. (2016) Identification of Synaptotagmin 10 as Effector of NPAS4-Mediated Protection from Excitotoxic Neurodegeneration. J. Neurosci. 36(9): 2561-2570.
  3. Becker AJ, Wiestler OD, Figarella-Branger D, Blümcke I, Capper D. Ganglioglioma. In: WHO Classification of Tumours of the Central Nervous System, Louis DN, Ohgaki H, Wiestler OD et al. (eds.), pp. 138-141, IARC: Lyon, 2016.
  4. Johnson MR*, et al.(…), Becker AJ*, Petretto E*. (2015) Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus. Nat. Commun., 6: 6031. doi: 10.1038/ncomms7031, 2015. (* co-corresponding authors)
  5. Kulbida R, Wang Y, Mandelkow EM, Schoch S, Becker AJ, van Loo KM. (2015) Molecular imaging reveals epileptogenic Ca2+-channel promoter activation in hippocampi of living mice.Brain Struct. Funct., 220(5): 3067-3073.
  6. Van Loo KMJ, Schaub C, Pitsch J, Kulbida R, Opitz T, Ekstein D, Dalal A, Urbach H, Beck H, Yaari Y, Schoch S, Becker AJ. (2015) Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1. Nat. Commun., Oct 26;6: 8688. doi: 10.1038/ncomms9688.
  7. Alvarez-Baron E, Michel K, Mittelstaedt T, Opitz T, Schmitz F, Beck H, Dietrich D, Becker AJ, Schoch S. (2013) RIM3γ and RIM4γ regulate neuronal arborization. J. Neurosci., 33: 824-839.
  8. Van Loo KM, Schaub C, Pernhorst K, Yaari Y, Beck H, Schoch S, Becker AJ. (2012) Transcriptional regulation of T-type calcium channel CaV3.2: bi-directionality by early growth response 1 (Egr1) and repressor element 1 (RE-1) protein-silencing transcription factor (REST). J. Biol. Chem., 287(19): 15489-15501.
  9. Becker AJ, Pitsch J, Sochivko D, Staniek M, Campbell KP, Schoch S, Yaari Y, Beck H. (2008) Transcriptional upregulation of Cav3.2 mediates epileptogenesis in the pilocarpine model of epilepsyJ. Neurosci., 28: 13341-13353.
  10. Fassunke J, Majores M, Tresch A, Niehusmann P, Grote A, Schoch S, Becker AJ. (2008) Array analysis of epilepsy-associated gangliogliomas reveals expression patterns related to aberrant development of neuronal precursors. Brain131: 3034-3050.

Mailing Address

Department of Neuropathology University of Bonn,
Medical School,
Sigmund-Freud-Str. 25,
D-53105 Bonn/Germany

Contact

Phone: +49-228 287 11352

Email: albert_becker@uni-bonn.de