Prof. Dr. rer. nat. Günter Mayer

Prof. Dr. rer. nat. Günter Mayer

Professor of Chemical Biology & Chemical Genetics (W3)

Weitere Informationen


2001 PhD degree (summa cum laude)
1998 – 2001 Dissertation at the LMU Munich and the University of Bonn
1998 Diploma in Chemsitry
1992 – 1998 Study of Chemistry at the LMU Munich

Academic positions

Since 2012 W3-Professor of Chemical Biology & Chemical Genetics, LIMES Institute, University of Bonn, Germany
2012 Offer for a position as Full Professor of Chemical Biology  at the Rjiksuniversiteit Groningen, Netherlands.
2010 W2-Professor of Chemical Biology & Chemical Genetics, LIMES Institute, University of Bonn, Germany.
2009 – 2010 Reader of Translational Biology at the University of Strathclyde, Glasgow, United Kingdom.
2009 Venia legendi in Molecular Biomedicine & Chemical Biology at the University of Bonn, Germany.
2004 – 2009 Group leader at the University of Bonn, LIMES Institute
2001 – 2004 Head of the Combinatorial Biotechnology Department and Co-founder of NascaCell Technologies AG, Munich, Germany

Memberships and professional functions

* Gesellschaft Deutscher Chemiker (GDCh), Gesellschaft für Biochemie und Molekularbiologie (GBM), Oligonucleotides Therapeutics Society (OTS)

Most important publications

  1. Seyfried P, Eiden L, Grebenovsky N, Mayer G, Heckel A. (2016) Photo-tethers for the (Multi-)cyclic, conformational caging of long oligonucleotides. Angew. Chem. Int. Ed. doi: 10.1002/anie.201610025.
  2. Jauset Rubio M, Svobodová M, Mairal T, Schubert T, Künne S, Mayer G, O’Sullivan CK. (2016) β-Conglutin dual aptamers binding distinct aptatopes. Anal Bioanal. Chem. 408, 875-84.
  3. Tolle F, Pfeiffer F, Rosenthal M, Mayer G. (2016) Click reaction on solid phase enables high fidelity synthesis of nucleobase-modified DNA. Bioconjug. Chem., 27, 500-503.
  4. Tolle F, Brändle GM, Matzner D, Mayer G. (2015) A Versatile Approach Towards Nucleobase-Modified Aptamers. Angew. Chem. Int. Ed.54:10971-4.
  5. Lennarz S, Alich TC, Kelly T, Blind M, Beck HMayer G. (2015) Selective aptamer-based control of intraneuronal signaling. Angew. Chem. Int. Ed., 54:5369-73.
  6. Opazo F, Eiden L, Hansen L, Rohrbach F, Wengel J, Kjems J, Mayer G. (2015) Modular Assembly of Cell-targeting Devices Based on an Uncommon G-quadruplex Aptamer. Mol. Ther. Nucleic Acids., 1, 4:e251.
  7. Rohrbach F, Schäfer F, Fichte MAH, Pfeiffer F, Müller J, Pötzsch B, Heckel A, Mayer G. (2013) Aptamer-guided caging for selective masking of protein domains. Angew. Chem. Int. Ed., 52, 1912-5.
  8. Müller J, Becher T, Braunstein J, Berdel P, Gravius S, Rohrbach F, Oldenburg J, Mayer G, Pötzsch B. (2011) Profiling of Active Thrombin in Human Blood by Supramolecular Complexes.Angew. Chem. Int. Ed.50, 6076–6078.
  9. Raddatz MS, Dolf A, Endl E, Knolle P, Famulok M, Mayer G. (2008) Enrichment of cell-targeting and population-specific aptamers by fluorescence-activated cell sorting. Angew. Chem. Int. Ed.47, 5190–5193.
  10. Heckel A, Mayer, G. Light-regulated aptamer: (2005) An anti-thrombin aptamer with caged thymidine nucleobases. J. Am. Chem. Soc.127, 822–823.


Phone: +49 (0)2 28 / 73 - 4808; +49 (0)2 28 / 73 – 4809