Senior group leader and University Professor
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Education/Degrees
| 1995 | B.Sc., Anatomy and Developmental Biology, University College London |
| 1995 | Degree, Biochemistry, FU Berlin |
| 1999 | Dr. rer. nat., Biology, Ruprecht-Karls-Universität Heidelberg |
| 2009 | Habilitation, Neurobiology, Ludwig-Maximilians-Universität München |
Academic Career
| 1995 – 1999 | PhD student, Cell Biology Program, EMBL, Heidelberg with Dr. C. Dotti |
| 2000 – 2002 | Postdoctoral research associate, University of California, San Francisco & Stanford University (both HHMI) with Prof. Dr. M. |
| Tessier-Lavigne (HFSP & EMBO Fellow) | |
| 2003 – 2011 | Independent junior Research Group Leader on associate Professor level (C3), Max-Planck Institute for Neurobiology, Martinsried |
| Since April 2011 | Senior Research Group Leader on Full Professor level (W3), German Center for Neurodegenerative Diseases (DZNE), Bonn |
| Since April 2011 | W3-Professor at the University of Bonn |
Awards and Honors
| 2000 | Long-Term Fellowship, EMBO, Heidelberg |
| 2001 | Long-Term Fellowship, Human Frontier Science Program, Strasbourg |
| 2003 | Career Development Award, Human Frontier Science Program, Strasbourg |
| 2007 | Selected Top 100 heads of tomorrow, Initiative of the Government of Germany |
| 2011 | Schellenberg-Prize, IRP, Switzerland |
| 2013 | Elected EMBO-Member |
| 2014 | Elected Leopoldina member, the German National Academy of Sciences |
| 2016 | Gottfried Wilhelm Leibniz-Preis |
Memberships, academic and professional functions
*Organizer of MPG meeting “Axon Degeneration”, Berlin 2014
*Organizer of EMBO workshop “Cell Biology of the Neuron”, Crete 2011
* Chair of the Cold Spring Harbor Meeting on Axon Guidance,Synapse Plasticity & Regeneration, 2010
* Organizer of the SFB-Symposium “Axon, Dendrites, Calcium channels” in 2006
* Organizer of the EU research training network meeting “Brain repair” in 2006
Most important publications
- Ruschel J, Hellal F, Flynn KC, Dupraz S, Elliott DA, Tedeschi A, Bates M, Sliwinski C, Brook G, Dobrindt K, Peitz M, Brüstle O, Norenberg MD, Blesch A, Weidner N, Bunge MB, Bixby JL,Bradke F. (2015). Systemic administration of epothilone B promotes axon regeneration and functional recovery. Science, 348: 347-352.
- Flynn KC, Hellal F, Neukirchen D, Jacobs S, Tahirovic S, Dupraz S, Stern S, Garvalov BK, Gurniak C, Shaw A, Meyn L, Wedlich-Söldner R, Bamburg JR, Small JV, Witke W, Bradke F.(2012). ADF/cofilin-mediated Actin Retrograde Flow Directs Neurite Formation in the Developing Brain. Neuron, 76: 1091-1107.
- Ertürk A, Mauch CP, Hellal F, Förstner F, Keck T, Becker K, Jährling N, Steffens H, Richter M, Hübener M, Kramer E, Kirchhoff F, Dodt HU, Bradke F. (2011) 3D imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury. Nature Medicine, 18: 166-171.
- Hellal F, Hurtado A, Ruschel J, Flynn KC, Laskowski CJ, Umlauf M, Kapitein LC, Strikis D, Lemmon V, Bixby J, Hoogenraad CC, Bradke F. (2011). Microtubule Stabilization Reduces Scarring and Causes Axon Regeneration After Spinal Cord Injury. Science, 331: 928-931.
- Neukirchen D, Bradke F. (2011). Cytoplasmic Linker Proteins Regulate Neuronal Polarization through Microtubule and Growth Cone Dynamics. J. Neurosci., 31: 1528-1538.
- Enes J, Langwieser N, Ruschel J, Carballosa-Gonzalez MM, Klug A, Traut MH, Ylera B, Tahirovic S, Hofmann F, Stein V, Moosmang S, Hentall ID, Bradke F. (2010). Electrical activity suppresses axon growth through Cav1.2 channels in adult primary sensory neurons. Current Biology, 20: 1154-1164.
- Tahirovic T, Hellal F, Garvalov BK, Chrostek-Grashoff A, Brakebusch C, Bradke F. (2010) Rac1 regulates neuronal polarization through the WAVE-complex. J. Neurosci., 30: 6930-6943.
- Stiess M, Maghelli M, Kapitein L, Gomis-Rüth S, Wilsch-Bräuninger M, Hoogenraad CC, Tolić-Nørrelykke IM, Bradke F. (2010). Axon extension occurs independently of centrosomal microtubule nucleation. Science, 327: 704-707.
- Ylera B, Ertürk A, Hellal F, Nadrigny F, Hurtado A, Tahirovic S, Oudega M, Kirchhoff F, Bradke F. (2009). Chronically injured adult sensory axons in the CNS acquire axon regenerative competence following a lesion of their peripheral process. Current Biology, 19: 930-936.Dispatch in Current Biology about this work.
- Ertürk A, Hellal F, Enes J, Bradke F. (2007). Disorganized microtubules underlie the formation of retraction bulbs and the failure of axonal regeneration. J. Neurosci., 27: 9169-9180.Commentaries in J. Neuroscience and Faculty of 1000.