Dr. Sandra Blaess

Dr. Sandra Blaess

Group Leader


Phone: +49-228 6885 540; +49-228 6885 501

Email: sandra.blaess@uni-bonn.de

Weitere Informationen

Education and degrees

1993 – 1996 Undergraduate studies in Molecular Biology (Biologie II), Biocenter, University of Basel
1997 – 2002 Dissertation in Cell Biology, Friedrich Miescher Institute for Biomedical Research and University of Basel. Fellowship of the Roche Research
2013  Habilitation, Faculty of Medicine, University of Bonn

Academic Career

2002 – 2006 Postdoctoral fellow at the Howard Hughes Medical Institute and Department of Developmental Genetics, Skirball Institute of Biomolecular
Medicine, New York University School of Medicine Postdoctoral fellowship of the German Research Foundation
2007 – 2008 Postdoctoral fellow at the Department of Developmental Biology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center
2008 – present Group leader of an independent research group, Neuro-developmental Genetics, Institute of Reconstructive Neurobiology, Medical Center Bonn
 2016 – present Heisenberg-Fellow of the DFG

Most important publications

  1. Gazea M, Tasouri M, Tolve M, Bosch V, Kabanova A, Gojak C, Kurtulmus B, Novikov O, Spatz J, Pereira G, Hübner W, Brodski C, Tucker KL, Blaess S. (2016)
Primary cilia are critical for Sonic hedgehog-mediated dopaminergic neurogenesis in the embryonic midbrain.
Dev. Biol., 409: 55-71.
  2. Kabanova A, Pabst M, Lorkowski M, Braganza O, Boehlen A, Nikbakht N, Pothmann L, Vaswani AR, Musgrove R, Di Monte A, Sauvage M, Beck H, Blaess S. (2015) Function and developmental origin of a mesocortical inhibitory circuit. Nat. Neurosci., 18: 872-882.
  3. Bodea GO, Spille JH, Abe P, Senturk Andersson A, Acker-Palmer A, Stumm R, Kubitscheck U,Blaess S. (2014) Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system. Development141: 661-673.
  4. Alvarez-Bolado G, Paul FA, Blaess S. (2012) Sonic hedgehog lineage in the mouse hypothalamus: From progenitor domains to hypothalamic regions. Neural Dev.7: 4.
  5. Blaess S*, Bodea GO, Kabanova A, Chanet S, Mugniery E, Derouiche A, Stephen D, Joyner AL. (2011) Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei. Neural Dev., 6: 29.
  6. Blaess S, Stephen D, Joyner AL. (2008) Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling. Development.135: 2093-2103.
  7. Corrales JD, Blaess S, Mahoney EM, Joyner, AL (2006) The level of Sonic hedgehog signaling regulates the complexity of cerebellar foliation. Development133: 1811-1821.
  8. Blaess S, Corrales JD, Joyner AL. (2006) Sonic hedgehog regulates Gli activator and repressor functions with spatial and temporal precision in the mid/hindbrain region.Development133: 1799-1809.
  9. Blaess S, Graus-Porta D, Belvindrah R, Radakovits R, Pons S, Littlewood-Evans A, Senften M, Guo H, Li Y, Miner JH, Reichardt LF, Müller U. (2004) b1-Integrins are Critical for Cerebellar Granule Cell Precursor Proliferation. J. Neurosci.24: 3402-3412.
  10. Graus-Porta DBlaess S, Senften M, Littlewood-Evans A, Damsky C, Huang Z, Orban P, Klein R, Schittny JC, Müller U. (2001) b1-class Integrins Regulate the Development of Laminae and Folia in the Cerebral and Cerebellar Cortex. Neuron31: 367-379.‡ equal contribution* corresponding author