University Professor, Vice Chair
Weitere Informationen
Education/Degrees
1988-1990 | Chemistry, University of Heidelberg, Prediploma (11/90) |
1990-1994 | Chemistry, University of Cologne, Diploma (04/94) |
1997 | PhD (11/97), Genetics, University of Cologne, Doctoral thesis advisor: Prof. G. Thiel |
Academic Career
1997 – 2002 | Post-doctoral fellow, Southwestern Medical Center at Dallas, Texas, USA, 2002, Prof. T.C. Südhof |
2003 – 2009 | Head of an independent research group at the Institute of Neuropathology, University of Bonn |
2003 – 2008 | Emmy Noether independent research group |
Since 2009 | Head of an independent research group funded by the BMBF |
Since 2009 | W2 professorship at the University of Bonn, Medical School |
Most important publications
- Pitsch J, Kamalizade D, Braun A, Kuehn JC, Gulakova PE, Rüber T, Lubec G, Dietrich D, von Wrede R, Helmstaedter C, Surges R, Elger CE, Hattingen E, Vatter H, Schoch S* and Becker AJ* (2020) Drebrin Autoantibodies in Patients with Seizures and Suspected Encephalitis. Ann. Neurol., 87: 869-884 *Corresponding author
- Poll S, Mittag M, Musacchio F, Justus LC, Giovannetti EA, Steffen J, Wagner J, Zohren L, Schoch S, Schmidt B, Jackson WS, Ehninger D, Fuhrmann M. (2020) Memory trace interference impairs recall in a mouse model of Alzheimer’s disease. Nat. Neurosci. 23(8):952-958.
- van Loo KMJ, Rummel CK, Pitsch J, Alexander Müller J, Bikbaev AF, Martinez Chavez E, Blaess S, Dietrich D, Heine M, Becker AJ, Schoch S (2019) Calcium channel subunit α2δ4 is regulated by early growth response 1 and facilitates epileptogenesis. J. Neurosci. 21:1731–18.
- Engholm-Keller K, Waardenberg AJ, Müller JA, Wark JR, Fernando RN, Arthur JW, Robinson PJ, Dietrich D, Schoch S, Graham ME (2019) The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation. PLoS Biol 17(3):e3000170. PMCID: PMC6415872
- Woitecki AMH, Müller JA, van Loo KMJ, Sowade RF, Becker AJ, Schoch S (2016) Identification of Synaptotagmin 10 as Effector of NPAS4-Mediated Protection from Excitotoxic Neurodegeneration. J. Neurosci. 36:2561–2570.
- Alvarez-Baron E, Michel K, Mittelstaedt T, Opitz T, Schmitz F, Beck H, Dietrich D, Becker AJ, Schoch S (2013) RIM3γ and RIM4γ regulate neuronal arborization. J. Neurosci. 33:824-839.
- Pitsch J, Opitz T, Woitecki A, Borm V, Staniek M, Beck H, Becker AJ, Schoch S (2012) The presynaptic active zone protein RIM1alpha controls epileptogenesis following status epilepticus. J. Neurosci. 32:12384-12395.
- Schoch S*, Mittelstaedt T, Kaeser PS, Padgett D, Feldmann N, Chevaleyre V, Castillo PE, Hammer RE, Han W, Schmitz F, Lin W, Südhof TC* (2006) Redundant functions of RIM1 and RIM2 in Ca2+-triggered neurotransmitter release. EMBO J. 25(24): 5852-5863. *Corresponding author
- Schoch S*, Castillo PE*, Jo T, Mukherjee K, Geppert M, Wang Y, Schmitz F, Malenka RC, Südhof TC (2002) RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature 415: 321-326. *equal contribution
- Schoch S, Deak F, Königstorfer A, Mozhayeva M, Sara Y, Südhof TC, Kavalali ET. (2001) SNARE function analyzed in synaptobrevin/VAMP knockout mice. Science. 294: 1117-1122.