Prof. Dr. Susanne Schoch McGovern

Prof. Dr. Susanne Schoch McGovern

University Professor, Vice Chair

Chair, Vice Chair, Executive Board, Principal Investigators

Weitere Informationen

Education/Degrees

1988-1990 Chemistry, University of Heidelberg, Prediploma (11/90)
1990-1994 Chemistry, University of Cologne, Diploma (04/94)
1997 PhD (11/97), Genetics, University of Cologne, Doctoral thesis advisor: Prof. G. Thiel

Academic Career

1997 – 2002 Post-doctoral fellow, Southwestern Medical Center at Dallas, Texas, USA, 2002, Prof. T.C. Südhof
2003 – 2009 Head of an independent research group at the Institute of Neuropathology, University of Bonn
2003 – 2008 Emmy Noether independent research group
Since 2009 Head of an independent research group funded by the BMBF
Since 2009 W2 professorship at the University of Bonn, Medical School

Most important publications

 

  1. Pitsch J, Kamalizade D, Braun A, Kuehn JC, Gulakova PE, Rüber T, Lubec G, Dietrich D, von Wrede R, Helmstaedter C, Surges R, Elger CE, Hattingen E, Vatter H, Schoch S* and Becker AJ* (2020) Drebrin Autoantibodies in Patients with Seizures and Suspected Encephalitis. Ann. Neurol., 87: 869-884 *Corresponding author
  2. Poll S, Mittag M, Musacchio F, Justus LC, Giovannetti EA, Steffen J, Wagner J, Zohren L, Schoch S, Schmidt B, Jackson WS, Ehninger D, Fuhrmann M. (2020) Memory trace interference impairs recall in a mouse model of Alzheimer’s disease. Nat. Neurosci. 23(8):952-958.
  3. van Loo KMJ, Rummel CK, Pitsch J, Alexander Müller J, Bikbaev AF, Martinez Chavez E, Blaess S, Dietrich D, Heine M, Becker AJ, Schoch S (2019) Calcium channel subunit α2δ4 is regulated by early growth response 1 and facilitates epileptogenesis. J. Neurosci. 21:1731–18.
  4. Engholm-Keller K, Waardenberg AJ, Müller JA, Wark JR, Fernando RN, Arthur JW, Robinson PJ, Dietrich D, Schoch S, Graham ME (2019) The temporal profile of activity-dependent presynaptic phospho-signalling reveals long-lasting patterns of poststimulus regulation. PLoS Biol 17(3):e3000170. PMCID: PMC6415872
  5. Woitecki AMH, Müller JA, van Loo KMJ, Sowade RF, Becker AJ, Schoch S (2016) Identification of Synaptotagmin 10 as Effector of NPAS4-Mediated Protection from Excitotoxic Neurodegeneration. J. Neurosci. 36:2561–2570.
  6. Alvarez-Baron E, Michel K, Mittelstaedt T, Opitz T, Schmitz F, Beck H, Dietrich D, Becker AJ, Schoch S (2013) RIM3γ and RIM4γ regulate neuronal arborization. J. Neurosci. 33:824-839.
  7. Pitsch J, Opitz T, Woitecki A, Borm V, Staniek M, Beck H, Becker AJ, Schoch S (2012) The presynaptic active zone protein RIM1alpha controls epileptogenesis following status epilepticus. J. Neurosci. 32:12384-12395.
  8. Schoch S*, Mittelstaedt T, Kaeser PS, Padgett D, Feldmann N, Chevaleyre V, Castillo PE, Hammer RE, Han W, Schmitz F, Lin W, Südhof TC* (2006) Redundant functions of RIM1 and RIM2 in Ca2+-triggered neurotransmitter release. EMBO J. 25(24): 5852-5863. *Corresponding author
  9. Schoch S*, Castillo PE*, Jo T, Mukherjee K, Geppert M, Wang Y, Schmitz F, Malenka RC, Südhof TC (2002) RIM1alpha forms a protein scaffold for regulating neurotransmitter release at the active zone. Nature 415: 321-326. *equal contribution
  10. Schoch S, Deak F, Königstorfer A, Mozhayeva M, Sara Y, Südhof TC, Kavalali ET. (2001) SNARE function analyzed in synaptobrevin/VAMP knockout mice. Science. 294: 1117-1122.

Contact

Phone: +49-228 287 19109; +49-228 287 19362

Email: Susanne.Schoch@uni-bonn.de

Website: http://www.meb.uni-bonn.de/neuropath/index.php?page=agschoch