News

The growth and migration of neurons in the brain are the focus of a recent study. As nerve cells form, they wire the brain to allow communication with other nerve cells. The axon, one of the wires that form when

A study led by the IEECR has identified a mechanism relying on Ste20-like kinase that allows single cortical neurons to cell-autonomously adjust feedforward inhibition they receive to the cell-specific levels of excitatory input. The authors propose that this mechanism is critical

Memory deficits are a debilitating symptom of epilepsy, but little is known about mechanisms underlying cognitive deficits. Here, we describe a Na+ channel-dependent mechanism underlying altered hippocampal dendritic integration, degraded place coding, and deficits in spatial memory. Two-photon glutamate uncaging experiments

Neurons Able to “Talk” Cannot Regenerate Adult neurons of the central nervous system do not regenerate if they are damaged, for example following a spinal cord injury. A study by DZNE researchers published in the scientific journal “Neuron” provides evidence

An inhibitory extracellular milieu and neuron-intrinsic processes prevent axons from regenerating in the adult central nervous system (CNS). Here we show how the two aspects are interwoven. Genetic loss-of-function experiments determine that the small GTPase RhoA relays extracellular inhibitory signals to the cytoskeleton by adapting mechanisms

We are happy and excited to announce that the DFG has  extended funding for the CRC 1089 for another 4 years. In the CRC 1089, BCN scientists together with partners from the DZNE and caesar, as well as national and