Neurons Able to “Talk” Cannot Regenerate Adult neurons of the central nervous system do not regenerate if they are damaged, for example following a spinal cord injury. A study by DZNE researchers published in the scientific journal “Neuron” provides evidence
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Frank Bradke awarded “Carl Zeiss Lecture”

Prof. Frank Bradke, research group leader at DZNE and a professor at the University of Bonn, will give this year’s “Carl Zeiss Lecture”. With this award, which has been presented since 1990, the German Society for Cell Biology (DGZ) recognizes outstanding
Read moreAG Bradke published an article about axon regeneration and astrocyte reactivity after CNS injury
An inhibitory extracellular milieu and neuron-intrinsic processes prevent axons from regenerating in the adult central nervous system (CNS). Here we show how the two aspects are interwoven. Genetic loss-of-function experiments determine that the small GTPase RhoA relays extracellular inhibitory signals to the cytoskeleton by adapting mechanisms
Read moreCRC 1089 extended
We are happy and excited to announce that the DFG has extended funding for the CRC 1089 for another 4 years. In the CRC 1089, BCN scientists together with partners from the DZNE and caesar, as well as national and
Read moreThe AG Schwarz developed a closed loop, deep learning-based real time posture detection tool allowing to autonomously conduct behavioral experiments.

The paper is published in Communications Biology. Title: Jens F. Schweihoff, Matvey Loshakov, Irina Pavlova, Laura Kück, Laura A. Ewell, Martin K. Schwarz (2021) DeepLabStream: Closing the loop using deep learning-based markerless, real time posture detection, Commun. Biol. Abstract:
Read moreA Protein that Pulls the Brake on Nerve Growth
Bonn/Germany, October 31, 2019. During embryonic development, nerve cells form thin, long extensions, which they use to wire up a complex network, the brain. Scientists from the German Center for Neurodegenerative Diseases (DZNE) in Bonn have now identified a protein
Read moreNew publication from Frank Bradke
SFB1089 member Prof. Bradke, who works at the German Center for Neurodegenerative Diseases (DZNE) and his group have identified a group of proteins that help to regenerate damaged nerve cells. Their findings are reported in the journal “Neuron”. It is
Read moreSFB1089 Member Frank Bradke to be awarded for research on neuronal regeneration
Bonn/Geneva, January, 30th, 2019. Frank Bradke, a senior researcher at the German Center for Neurodegenerative Diseases (DZNE) and a professor at the University of Bonn, will be awarded the Roger de Spoelberch Prize, which is endowed with 750,000 euros. The Swiss Roger
Read moreStefan Remy receives “CONSOLIDATOR GRANT”

Stefan Remy will receive the “Consolidator Grant” from the European Research Council worth 1.8 million. More information you can find here.
Read moreRabies viruses reveal wiring in transparent brains

Scientists under the leadership of the University of Bonn have harnessed rabies viruses for assessing the connectivity of nerve cell transplants: coupled with a green fluorescent protein, the viruses show where replacement cells engrafted into mouse brains have connected to
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