Dr. Jan Gründemann

Dr. Jan Gründemann



Phone: +49 228 433 02 778

Email: jan.grundemann@dzne.de


2001 – 2006 Diploma in Human Biology, University of Marburg, Medical School
2011 Doctoral thesis, Prof. Michael Häusser, University College London, UK


Academic Career:

2011 – 2014



Postdoctoral Fellow, Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland

Visiting Scientist, Stanford University, Stanford, USA

2015 – 2017 Ambizione Fellow, Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland
Since 2018 SNF Professor, University of Basel, Switzerland
Since 10/2020 Group Leader, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany


Awards and Honors:

2020                 Forschungspreis der Schweizerischen Hirnliga (shared, CHF 20’000)

2018                 ERC starting grant, European Research Council (EUR 1’475’475)

2017                 Swiss National Science Foundation Professorship (CHF 1’552’618)

2017                 Wellcome Trust Sir Henry Dale Fellowship (awarded, not taken, GBP 1’469’034)

2016                 King’s College London Prize Fellowship (awarded, not taken, GBP 140’000)

2014                 Ambizione Fellowship, Swiss National Science Foundation (CHF 562’149)

2012                 EMBO Long-Term Fellowship (CHF 125’171)

2006                 Wellcome Trust PhD Studentship (GBP 151’326)

Memberships, academic and professional duties (selection):

Since 2019       Cold Spring Harbor Laboratories, USA (Instructor ‘Ion Channel Physiology’ Course)

2019                 International Neuroscience Winter Conference Sölden, Austria, Co-organizer of symposium

2018                 FENS Neuroscience Meeting 2018, Berlin, Germany, Co-organizer of symposium (S06)

List of 10 most important publications

  1. a) Published
  2. Gründemann J*, Bitterman Y*, Lu T, Krabbe S, Grewe BF, Schnitzer MJ, Lüthi A. (2019) Amygdala ensembles encode behavioral states. Science, 364(6437): eaav8736.
  3. Krabbe S, Paradiso E, d’Aquin S, Bitterman Y, Courtin J, Xu C, Yonehara K, Markovic M, Müller C, Eichlisberger T, Gründemann J*, Ferraguti F*, Lüthi A*. (2019) Adaptive disinhibitory gating by VIP interneurons permits associative learning. Neurosci., 22(11): 1834-1843.
  4. Grewe BF, Gründemann J, Kitch LJ, Lecoq JA, Parker JG, Marshall JD, Larkin MC, Jercog PE, Grenier F, Li JZ, Lüthi A, Schnitzer MJ. (2017) Neural Ensemble Dynamics Underlying a Long-Term Associative Memory. Nature, 543(7647): 670-675.
  5. Xu C, Krabbe S, Gründemann J, Botta P, Fadok JP, Osakada F, Saur D, Grewe BF, Schnitzer MJ, Callaway EM, Lüthi A. (2016) Distinct Hippocampal Pathways Mediate Dissociable Roles of Context in Memory Retrieval. Cell, 167(4): 961-972.e16.
  6. Vogel E, Krabbe S, Gründemann J, Wamsteeker Cusulin JI, Lüthi A. (2016) Projection-Specific Dynamic Regulation of Inhibition in Amygdala Micro-Circuits. Neuron, 91(3): 644-51.
  7. Gründemann J, Lüthi A. (2015) Ensemble coding in amygdala circuits for associative learning. Curr Opin Neurobiol, 35: 200-6.
  8. Gründemann J, Clark BA. (2015) Calcium-Activated Potassium Channels at Nodes of Ranvier Secure Axonal Spike Propagation. Cell Rep., 12(11): 1715-22.
  9. Wolff SB*, Gründemann J*, Tovote P, Krabbe S, Jacobson GA, Müller C, Herry C, Ehrlich I, Friedrich RW, Letzkus JJ, Lüthi A. (2014) Amygdala interneuron subtypes control fear learning through disinhibition. Nature, 509(7501): 453-8.
  10. Gründemann J, Schlaudraff F, Haeckel O, Liss B. (2008) Elevated Alpha-Synuclein mRNA Levels in Individual UV-laser-microdissected Dopaminergic Substantia Nigra Neurons in Idiopathic Parkinson’s Disease. Nucleic Acids Res., 36(7): e38.
  11. b) Preprints
  12. Taylor JA, Hasegawa M, Benoit CM, Freire JA, Theodore M, Ganea DA, Lu T, Gründemann J. (2020) Single cell plasticity and population coding stability in auditory thalamus upon associative learning. bioRxiv, https://doi.org/10.1101/2020.04.06.02640