Project leader
Contact
Phone: +49-228 9656-327
Education and degrees
| 1992 – 1997 | Studies in Biology, Universities of Giessen and Cologne |
| 1997 | Diploma in Biology |
| 1997 – 2000 | Ph.D. thesis at Max-Planck-Institute for Molecular Physiology |
| 2000 | PH.D. University of Cologne |
Academic Career
| 2001 – 2004 | Postdoctoral fellow, Division of Protein Structure (Group of Katrin Rittinger), NIMR, London, UK |
| 2005 – 2009 | Emmy Noether Group Leader, Department of Biomolecular Mechanisms, Max-Planck-Institute for Medical Research, Heidelberg |
| 2010 – 2014 | Minerva Group Leader, Max-Planck-Institute for Developmental Biology, Tuebingen |
| Since 2014 | Research Associate at Research center Caesar, Bonn |
Awards an honors
| 2000 | ‘Summa cum laude’ for PH.D. thesis work |
| 2001 | Emmy Noether postdoctoral fellowship |
| 2004 | Emmy Noether Independent junior research group fellowship |
Memberships and professional functions
- German society for Biochemistry and molecular Biology
- German society for Cell Biology
Most important publications
- Wuertenberger S, Groemping Y. (2015) A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domains. FEBS Letter 589:1156-63.
- Kintscher C, Wuertenberger S, Eylenstein R, Uhlendorf T, Groemping Y. (2010) Autoinhibition of GEF activity in Intersectin 1 is mediated by the short SH3-DH domain linker. Protein Sci19:2164-74.
- Rump J, Simon B, Jung N, Maritzen T, Haucke V, Sattler M, Groemping Y. (2008) Structure of the Eps15-stonin2 complex provides a molecular explanation for EH domain ligand specificity.EMBO J. 27: 558-569.
- Groemping Y, Rittinger K (2005) Activation and assembly of the NADPH oxidase: a structural perspective. Biochem J 386: 401-416.
- Groemping Y, Lapouge K, Smerdon SJ and Rittinger K (2003) Molecular basis of phosphorylation-induced activation of the NADPH oxidase. Cell 113: 343-55.