Dr. Yvonne Groemping

Dr. Yvonne Groemping

Project leader


Phone: +49-228 9656-327

Education and degrees

1992 – 1997 Studies in Biology, Universities of Giessen and Cologne
1997 Diploma in Biology
1997 – 2000 Ph.D. thesis at Max-Planck-Institute for Molecular Physiology
2000 PH.D. University of Cologne


Academic Career

2001 – 2004 Postdoctoral fellow, Division of Protein Structure (Group of Katrin Rittinger), NIMR, London, UK
2005 – 2009 Emmy Noether Group Leader, Department of Biomolecular Mechanisms, Max-Planck-Institute for Medical Research, Heidelberg
2010 – 2014 Minerva Group Leader, Max-Planck-Institute for Developmental Biology, Tuebingen
Since 2014 Research Associate at Research center Caesar, Bonn

Awards an honors

2000 ‘Summa cum laude’ for PH.D. thesis work
2001 Emmy Noether postdoctoral fellowship
2004 Emmy Noether Independent junior research group fellowship


Memberships and professional functions

  • German society for Biochemistry and molecular Biology
  • German society for Cell Biology

Most important publications

  1. Wuertenberger S, Groemping Y. (2015) A single PXXP motif in the C-terminal region of srGAP3 mediates binding to multiple SH3 domainsFEBS Letter 589:1156-63.
  2. Kintscher C, Wuertenberger S, Eylenstein R, Uhlendorf T, Groemping Y. (2010) Autoinhibition of GEF activity in Intersectin 1 is mediated by the short SH3-DH domain linker. Protein Sci19:2164-74.
  3. Rump J, Simon B, Jung N, Maritzen T, Haucke V, Sattler M, Groemping Y. (2008) Structure of the Eps15-stonin2 complex provides a molecular explanation for EH domain ligand specificity.EMBO J. 27: 558-569.
  4. Groemping Y, Rittinger K (2005) Activation and assembly of the NADPH oxidase: a structural perspective. Biochem J 386: 401-416.
  5. Groemping Y, Lapouge K, Smerdon SJ and Rittinger K (2003) Molecular basis of phosphorylation-induced activation of the NADPH oxidase. Cell 113: 343-55.